The most effective way of using hyaluronic acid on the face is by injecting it into deep wrinkles and naso-labial folds. Hyaluronic acid is the main ingredient in Restylane---a gel-like substance that dermatologists inject into moderate and severe wrinkles to plump them up. This anti-aging medication must be prescribed and administered by a dermatologist. It is a noninvasive procedure with a quick recovery time.

Restylane is the only FDA-approved wrinkle filler on the market. It adds volume into depressed wrinkles to smooth and lift them. It also locates water molecules in the cells to bind them to the skin and promote volume. Within six months after the initial injection, the body absorbs the hyaluronic acid and it eventually dissipates. At this point, you would need another injection to keep wrinkles at bay.